2023
- Kahler JP, Aloi D, Miedes Aliaga J, Kerselaars S, Voets T, Vriens J, Verhelst SHL, Barniol-Xicota M. Clotrimazole-based modulators of the TRPM3 ion channel reveal narrow structure-activity relationship. ACS Chem Bio. 2023, 18, 3, 456–464. DOI: 10.1021/acschembio.2c00672
- Vanhoutte R, Barniol-Xicota M, Chiu W, Vangeel L, Jochmans D, De Jonghe S, Zidane H, Barr HM, London N, Neyts J, Verhelst SHL. Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells. Chem Sci. 2023 Jan 6;14(7):1666-1672. doi: 10.1039/d2sc04147b.
2022
2021
- Barniol-Xicota M. & Verhelst SHL. Lipidomic and in-gel analysis of maleic acid co-polymer-based nanodiscs reveals differences in composition of solubilized membranes. Commun. Biol. 4, 218, 2021.
2020
- van de Plassche MAT*, Barniol-Xicota M*, Verhelst SHL. Peptidyl Acyloxymethyl Ketones as Activity-Based Probes for the Main Protease of SARS-CoV-2. Chembiochem. 2020; doi:10.1002/cbic.202000371. *Shared first-authorship. Journal Cover
- Barniol-Xicota M & Verhelst SHL. Isolation of intramembrane proteases in membrane-like environments. Biochim Biophys Acta Biomembr. 2020;1862(4):183193.
2019
- Beard H A, Barniol-Xicota M, Yang J, Verhelst SHL. Discovery of Cellular Roles of Intramembrane Proteases. ACS Chem Biol. 2019;14(11):2372-2388. doi:10.1021/acschembio.9b00404
- Perez-Areales FJ, Turcu A, Barniol-Xicota M, Pont C, Pivetta D, Espargaró A, Bartolini M, De Simone A, Andrisano V, Pérez B, Sabaté R, Sureda FX, Vázquez S, Muñoz-Torrero D. A novel class of multitarget benzohomoadamantane-chlorotacrine hybrids to confront the cholinergic and glutamatergic mechanisms of Alzheimer’s disease. Eur. J. Med. Chem. 2019 180 613-626.
2018
- Barniol-Xicota M. & Verhelst S. H. L. Functional Rhomboid Proteases in Lipid Nanodiscs by Using Diisobutylene/Maleic Acid Copolymers. J Am Chem Soc 2018 140 44 14557-14561.
- Alonso JM, Quiroga S, Codony S, Turcu AL, Barniol-Xicota M, Pérez D, Guitián E, Vázquez S, Peña D. Palladium-catalyzed Cocyclotrimerization of Arynes with a Pyramidalized Alkene. Chem Comm. 2018 54(47):5996-5999.
- Yang J, Barniol-Xicota M, Nguyen MTN, Ticha A, Strisovsky K, Verhelst SHL. Benzoxazin-4- ones as novel easily accessible inhibitors for rhomboid proteases. Bioorg Med Chem. 2018 28 (8) 1423-1427.
- Karoutzou O, Kwak S-H, Lee S-D, Martínez-Falguera D, Sureda FX, Vázquez S, Kim Y-C, Barniol-Xicota M. Multi-target directed ligands to the NMDA and P2X7 receptors of interest for the treatment of Alzheimer’s disease. Molecules 2018 23(1) 230.
- Leiva R, Barniol-Xicota M, Codony S, Ginex T, Vanderlinden E, Montes M, Caffrey M, Luque FJ, Naesens L, Vázquez S. Aniline-based inhibitors of influenza H1N1 virus acting on hemagglutinin-mediated fusion. J Med Chem. 2018 61(1) 98-118.
2017
- Rao ZX, Patel B, Monaco A, Cao ZJ, Barniol-Xicota M., Pichon E, Ladlow M, Hilton ST. 3D-Printed polypropylene continuous-flow column reactors: exploration of reactor utility in SNAr reactions and the synthesis of bicyclic and tetracyclic heterocycles. Eur J Org Chem. 2017 44 6499-6504.
- Barniol-Xicota M, Gazzarrini S, Torres E, Naesens L, Moroni A, Wang J, Vázquez S. Slow but steady wins the race: dissimilarities among new dual inhibitors of the wild-type and the V27A mutant M2 channels of influenza A virus. J Med Chem. 2017 60(9) 3727-3738.
- Lin C-W, Mensa B, Barniol-Xicota M, DeGrado WF, Gai F. Activation pH and Gating Dynamics of Influenza A M2 Proton Channel Revealed by Single-Molecule Spectroscopy. Angew Chem Int Ed. 2017. 56(19)5283-5287.
- Monaco A, Szulc BR, Rao ZX, Barniol-Xicota M, Sehailia M, Borges B, Hilton S. A Short Total Synthesis of (±)-Lycorane by a Sequential Intramolecular Acylal Cyclisation (IAC) and Intramolecular Heck Addition Reaction. Chemistry. 2017 23(20) 4750-4755.
- Barniol-Xicota M, Kwak S-H, Lee S-D, Caseley E, Valverde E, Kim YC, Vázquez S. Escape from adamantane: scaffold optimization of novel P2X7 antagonists featuring complex polycycles. Bioorg Med Chem Lett. 2017 27 759- 763.
2016
- Zarei M, Barroso E, Leiva R, Barniol-Xicota M, Pujol-Bech E, Escolano C,Vázquez S, Palomer X, Pardo V, González-Rodríguez A, Valverde AM, Quesada T, Villarroya F, Wahli W, Vázquez-Carrera M. Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and is Activated by PPARβ/δ Deficiency. Diabetes. 2016 65(10)3185-99.
- Barniol-Xicota M, Leiva R, Escolano C, Vázquez S. Syntheses of Cinacalcet: An Enantiopure Active Pharmaceutical Ingredient (API). Synthesis 2016. 48 783-803.
2015
2014
- Rey-Carrizo M, Barniol-Xicota M, Font-Bardia M, Vázquez S. Dimerization of Pyramidalized 3,4,8 9-Tetramethyltetracyclo [4.4.0.0(3 9).0(4 8)]dec-1(6)-ene to a Hydrocarbon Featuring Four Cyclohexane Rings in Boat Conformations. Angew Chem Int Ed. 2014, 53, 8195-8199.
- Rey-Carrizo M, Barniol-Xicota M, Ma C, Frigolé-Vivas M, Torres E, Naesens L, Llabrés S, Juárez-Jiménez J, Luque FJ, DeGrado WF, Lamb RA, Pinto LH, Vázquez S. Easily Accessible Polycyclic Amines that Inhibit the Wild-Type and Amantadine-Resistant Mutants of the M2 Channel of Influenza A Virus. J Med Chem. 2014. 57(13) 5738-5747.
- Barniol-Xicota M, Turcu AL, Codony S, Escolano C, Vázquez S. Direct reductive alkylation of amine hydrochlorides with aldehyde bisulfite adducts. Tetrahedron Lett. 2014. 55 2548-2550.
2013